A UK prospective cohort study suggested that habitual use of glucosamine supplement to relieve osteoarthritis pain might also be related to lower risks of cardiovascular diseases (CVD) events. The study enrolled 466 039 participants from 2006 to 2010. During a median follow-up of 7 years, there were 10 204 incident CVD events, 3060 CVD deaths, 5745 coronary heart disease events, and 3263 stroke events. After adjustment for age, sex, body mass index, race, lifestyle factors, dietary intakes, drug use, and other supplement use, glucosamine use was associated with a significantly lower risk of total CVD events (hazard ratio 0.85), CVD death (0.78), coronary heart disease (0.82), and stroke (0.91). The findings are in line with several previous studies and suggest that glucosamine might have a preventive role in CVD through anti-inflammatory and mimicking a low carbohydrate diet properties. Source: https://www.bmj.com/
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