A blinded, multicenter randomized trial of percutaneous coronary intervention (PCI) versus a sham procedure for angina relief in the UK revealed that in patients with medically treated angina and severe coronary stenosis, PCI did not increase exercise time or improve symptoms. 230 patients with ischemic symptoms and severe (≥70%) single-vessel stenosis were enrolled and received 6 weeks of medication optimization, 200 patients underwent randomization between Jan 6, 2014, and Aug 11, 2017. Lesions had mean area stenosis of 84·4%, fractional flow reserve of 0·69, and instantaneous wave-free ratio of 0·76. There was no significant difference in the primary endpoint of exercise time increment between groups (PCI minus placebo 16·6 s, 95% CI −8·9 to 42·0, p=0·200). The results are consistent with previous findings that PCI in stable lesions did not produce long-term improvements in outcome when compared to optimal medical therapy. PCI has been proven effective in acute coronary syndrome. Source: http://www.thelancet.com/
A U.S. randomized clinical trial found that 4:3 intermittent fasting (IMF) led to slightly greater…
A Danish nationwide cohort study provided real world evidence that both glucagon-like peptide 1 receptor…
A systematic review and meta-analysis of placebo-controlled randomized trials showed that there is moderate certainty…
A US cohort study indicated that statin use may reduce the risks of hepatocellular carcinoma…
A US cohort study suggests that carotid artery plaque (CAP) becomes very common with increasing…
A prospective US population-based cohort study suggested that higher intake of butter was associated with…
This website uses cookies.