Prostate Cancer

Pros and Cons of PSA Screening for Prostate Cancer

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An updated Cochrane systematic review of five randomized controlled trials involving 341,342 men found that PSA-based prostate cancer screening did not significantly reduce prostate cancer-specific mortality or overall mortality when all studies were combined, although one major European study (ERSPC) showed a 21% reduction in prostate cancer deaths among men […]

Active Surveillance Safe and Effective for Low-Risk Prostate Cancer

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A prospective multicenter cohort study revealed that protocol-directed active surveillance is safe and effective for avoiding overtreatment and preventing undertreatment in patients with low-risk prostate cancer. The study included 2155 patients with favorable-risk prostate cancer and no prior treatment from 2008 to 2022 with a median follow-up of 7.2 years. […]