A comprehensive new Cochrane review of 22 studies involving nearly 2,000 participants over six months to one year has found that intermittent fasting may offer little to no significant benefit over standard dietary advice for weight loss in people with overweight or obesity. When compared to regular, calorie-restricted diet plans, […]
A U.S. randomized clinical trial found that 4:3 intermittent fasting (IMF) led to slightly greater weight loss than daily caloric restriction (DCR) in adults with overweight or obesity. The study included 165 participants (mean age: 42; mean BMI: 34.1 kg/m²; 73.9% female), randomly assigned to either 4:3 IMF (n=84) or […]
A randomized, open-label, active parallel-controlled clinical trial showed that 2 nonconsecutive fasting days (with a daily energy intake of 500 kcal for women and 600 kcal for men) and 5 days of habitual intake per week and meal replacement diet (5:2 MR) achieved better glycemic control compared with metformin and […]