Definition


2026 Fifth Universal Definition of Myocardial Infarction

The Fifth Universal Definition of Myocardial Infarction (MI) updates the classification of MI by defining three major clinical settings—primary MI, secondary MI, and procedure-related MI—to better reflect underlying pathophysiology, support clinical evaluation, and incorporate objective diagnostic criteria. Primary MI occurs spontaneously because of an acute coronary pathology; although most cases […]


2026 Second Universal Definition of Heart Failure

The Second Universal Definition of Heart Failure (HF) introduces a standardized global framework that updates how HF is defined, classified, prevented, and managed, with the goal of improving patient care and cardiovascular health worldwide. Recognizing the growing burden of HF and the limitations of previous definitions, international cardiac societies and […]