Healthy Diet Linked to Lower Cancer Risk

A French prospective population-based cohort study suggests that healthy diet by following dietary recommendations could significantly contribute to cancer prevention. The study investigated the associations between several nutritional scores and overall, breast, prostate, and colorectal cancer risk in a large prospective population-based cohort. The study included 41,543 participants aged ≥40 […]


Midlife Orthostatic Hypotension Linked to Dementia and Stroke

An US prospective cohort study revealed that orthostatic hypotension (OH) in midlife was independently associated with incident dementia and ischemic stroke. The study included 11,709 participants without a history of coronary heart disease or stroke at the baseline examination (1987–1989, mean age 54). OH was defined as a drop in […]


Intermittent Diet Comparable to Continuous Diet for T2D

A randomized noninferiority trial in Australia suggested that intermittent energy restriction is an effective alternative diet strategy for the reduction of hemoglobin A1c (HbA1c) level comparable to continuous energy restriction in patients with type 2 diabetes (T2D), and it may be superior to continuous energy restriction for weight loss. The […]


Water Drinking Effective for Orthostatic Hypotension

An UK study found that bolus water drinking is superior to other nonpharmacological interventions for older people with orthostatic hypotension (OH). A total of 150 orthostatic challenges were performed in 25 older people (age 60–92 years). The response rate (of participants whose systolic blood pressure [SBP] drop improved by ≥10 […]


Reflex Syncope

Reflex syncopes include vasovagal, carotid sinus, and situational syncope, share a common pathophysiology: an abrupt slowdown of the heart rate and a dilatation of the blood vessels leading to hypo-perfusion of the brain. Pain, seeing blood, emotional reaction, and prolonged standing are triggers of vasovagal syncope. Situational is triggered by […]


Genetic Association Estimate for Lipoprotein(a)-Lowering Therapies

A mendelian randomization analysis revealed that Lipoprotein(a) [ Lp(a)]concentration must be lowered by approximately 100 mg/dL to achieve the same reduction in coronary heart disease (CHD) risk as can be achieved by lowering low-density lipoprotein cholesterol (LDL-C) level by 38.67 mg/dL. The analysis involved more than 80 000 patients and more […]