Silent MI Deadly

A population-based, prospective cohort study in Iceland revealed that the long-term mortality risk of unrecognized myocardial infarction (UMI) can be as high as clinically recognized myocardial infarction (RMI). 935 participants (aged 67-93 years, 48.3% men) were characterized with cardiac magnetic resonance (CMR) from January 2004 to January 2007 and followed […]


Cannabis Use May Cause Cognitive Impairments

A longitudinal randomized controlled trial in Canada revealed that concurrent and lasting effects of adolescent cannabis use can be observed on important cognitive function and appear to be more pronounced than those observed for alcohol. The study included a population-based sample of 3,826 seventh-grade students from 31 schools consisting of […]


Aspirin for Primary Prevention Challenged

Findings of two randomized, placebo controlled clinical trials challenged the role of aspirin in primary prevention in a low-risk population and in patients of diabetes. A randomized, double-blind, placebo-controlled, multicenter study was done in seven countries. Between July 5, 2007, and Nov 15, 2016, 12 546 eligible patients aged 55 years […]


Glutamine Effective and Safe in IBS-D

A small randomized, double-blind, placebo-controlled trial in the US showed that oral dietary glutamine supplements effective and safe in patients with diarrhea-predominant irritable bowel syndrome (IBS-D) with intestinal hyperpermeability following an enteric infection. Participants (mean age 31.7, approximately 70% women, and 80% white) were randomized to glutamine (5 g/t.i.d.) or placebo […]