Meal-Induced Inflammation

A UK single-arm dietary intervention study suggests that postprandial inflammation is largely driven by acute elevations in circulating triglyceride (TG). Glycoprotein acetylation (GlycA) after mixed meals may be a promising candidate biomarker for assessing the food-induced inflammatory response within typical dietary habits. The study included 1002 healthy adults aged 18–65 […]


A Novel Circulating MicroRNA for Myocarditis Diagnosis

A novel microRNA has been identified in mice and humans with myocarditis, and that the human homologue could be used to distinguish patients with myocarditis from those with myocardial infarction. The human homologue, designated hsa-miR-Chr8:96, was identified in four independent cohorts of patients with myocarditis. The area under the receiver-operating-characteristic […]


2021 Guideline for the Secondary Prevention of Stroke

The 2021 secondary stroke prevention guideline from the American Heart Association/American Stroke Association: 1. Recommendations for the diagnostic workup to define ischemic stroke etiology. 2. Management of vascular risk factors remains extremely important, including (but not limited to) diabetes, smoking cessation, lipids, and especially hypertension. 3. Lifestyle factors: Low-salt and […]


Medication May Be Offered for Mild High Blood Pressure

Both a scientific statement from the American Heart Association and an individual participant-level data meta-analysis support that pharmacological blood pressure (BP) lowering is effective for primary and secondary prevention of major cardiovascular disease (CVD), even at BP levels currently not considered for treatment. The statement provides evidence suggesting that in […]


Thiazides Linked to Skin Cancer Risk

A Canadian population-based cohort study revealed dose-dependent increases in skin cancer risk associated with thiazides in people aged 66 years and older. The study included a total of 302 634 adults aged ≥ 66 years prescribed an antihypertensive medication and 605 268 matched unexposed adults. Increasing thiazide exposure was associated […]


Covid Vaccine-Associated Immune Thrombotic Thrombocytopenia

Rare and unusual adverse thrombotic events and thrombocytopenia may be associated with COVID-19 vaccines from AstraZeneca and Johnson & Johnson (J&J), so called vaccine-associated immune thrombotic thrombocytopenia (VITT). VITT resembles autoimmune heparin-induced thrombocytopenia, a well-known prothrombotic disorder caused by platelet-activating antibodies that recognize multimolecular complexes between cationic platelet factor 4 […]