Daily Archives: May 4, 2024

GWAS Improved BP Polygenic Risk Scores

This entry was posted in Cardiovascular Diseases and tagged BP GWAS Polygenic Risk Scores on by

A single-stage common-variant genome-wide association study (GWAS) of blood pressure (BP) in European-ancestry adults improved BP polygenic risk scores (PRS) and provided additional insights into the genetic contribution of BP. The study identified 113 novel loci, reporting a total of 2,103 independent genetic signals in 1,028,980 European individuals from the […]

Effects of Menopausal Hormone Therapy, Calcium Plus Vitamin D Supplementation, and Dietary Modification

This entry was posted in Cardiovascular Diseases Health Uncategorized and tagged Calcium Diet Hormone Therapy Menopause Vitamin D on by

The US Women’s Health Initiative (WHI) clinical trial results do not support hormone therapy with oral conjugated equine estrogens plus medroxyprogesterone acetate for postmenopausal women or conjugated equine estrogens alone for those with prior hysterectomy to prevent cardiovascular disease, dementia, or other chronic diseases. However, hormone therapy is effective for […]