The UK National Institute for Health and Care Excellence (NICE) has updated the guideline on management of depression with new recommendations. In the new guideline, depression is classified as “less severe” and “more severe”. More severe includes moderate and severe, and less severe includes mild and sub-threshold depression. Sub-threshold has […]
A systematic review and network meta-analysis provided the most comprehensive data synthesis on pharmacological treatments for adults with insomnia. The study included 170 trials (36 interventions and 47 950 participants) in the systematic review and 154 double-blind, randomized controlled trials (30 interventions and 44 089 participants) for the network meta-analysis. Benzodiazepines, doxylamine, […]
A UK cohort study and Mendelian randomization (MR) suggested that moderate alcohol consumption [>7 units (56 g) alcohol weekly] was associated with markers of higher brain iron and worse cognitive function. The study included 20,729 UK Biobank participants (mean age 54.8 years, 48.6% female). Multiorgan susceptibility-weighted magnetic resonance imaging (~9.60 […]
A prospective study indicates that the higher frequency of adding salt to foods is associated with a higher risk of all-cause premature mortality and lower life expectancy. The study included 501 379 participants from UK biobank. There were graded relationships between higher frequency of adding salt to foods and higher concentrations […]