Monthly Archives: November 2019


Falls and TBI in the Elderly

Dr. Bermanand Dr. Boguskisummarized the risk factors for falls in the elderly and traumatic brain injury (TBI). Risk factors for falls include lower body weakness; past history of a fall; difficulties with walking and balance; use of medicines, such as tranquilizers, sedatives, or antidepressants and medicines affect balance; vision problems; […]


Medication on Par with Early Invasive Treatment for Stable IHD

An international randomized trial revealed that an initial invasive approach compared to optimal medical therapy (OMT) in stable ischemic heart disease (SIHD) patients with moderate-severe ischemia did not reduce risk of cardiovascular disease (CVD) end points at a median of 3.3 years. The trial enrolled 5179 SIHD patients with moderate-severe ischemia […]


Low-Dose Colchicine Effective in CVD

A randomized, double-blind trial in Canada concluded that among patients with a recent myocardial infarction (MI), colchicine at a dose of 0.5 mg daily led to a significantly lower risk of ischemic cardiovascular events than placebo.A total of 4745 patients within 30 days after a MI were randomly assigned to […]


Lower Blood Pressure Might Reduce Dementia Risk

A meta-analysis of individual participant data from eligible observational studies suggested that use of any antihypertensive medications (AHM) with efficacy to lower blood pressure (BP) might reduce the risk for dementia among people with high BP. However, no evidence was found that a specific AHM drug class was more effective […]


Early Life Vascular Risk Linked to Brain Pathology Later

A prospective longitudinal cohort study in Britain revealed that early adulthood vascular risk is strongly associated with smaller whole-brain volume (WBV) and greater white matter–hyperintensity volume (WMHV) at age 69 to 71 years. The study assessed 502 participants in a birth cohort in 1946. Framingham Heart study–cardiovascular risk scores (FHS-CVS) […]