Cardiovascular Diseases

The Higher Life’s Simple 7 Scores, The Lower Dementia Risk Across Genetic Profiles

A study of incident dementia, midlife Life’s Simple 7 (LS7) scores and generated genetic risk scores (GRS) using genome-wide summary…

3 years ago

Prevalence and Clinical Significance of DNA Variants Predisposing to Cardiomyopathy

A genetic association study indicates that 0.7% of participants harbor a pathogenic variant related to inherited cardiomyopathy and are at…

3 years ago

Aspirin Use to Prevent CVD Updated

The US Preventive Services Task Force recommends against initiating low-dose aspirin use for the primary prevention of cardiovascular disease (CVD)…

3 years ago

SGLT2 Inhibitor’s Heart Benefit Extended

A systematic review and meta-analysis concluded that sodium–glucose cotransporter-2 (SGLT2) inhibitors reduced hospitalizations for heart failure (HF) regardless of the…

3 years ago

Treatment for Mild Chronic Hypertension during Pregnancy Beneficial

A US open-label, multicenter, randomized trial concluded that in pregnant women with mild chronic high blood pressure (BP), a strategy…

3 years ago

Statin Benefits Modest

A systematic review and meta-analysis suggests that the absolute benefits of statins are modest and may not be strongly mediated…

3 years ago

Intensive BP Control Increased Brain Blood Flow

A substudy of the randomized clinical trial compared intensive vs standard systolic blood pressure (SBP) control revealed that the intensive…

3 years ago

Sodium-containing Acetaminophen Linked to CVD Risk

Two UK cohort studies among individuals with and without high blood pressure (HBP) found that the initiation of sodium-containing acetaminophen…

3 years ago

Leg Muscle Preactivation and Tensing Mitigate initial Orthostatic Hypotension

A Canadian study demonstrated that preactivating lower body muscle (PREACT) and leg crossing with muscle tensing (TENSE) after standing attenuates…

3 years ago

Acetaminophen Increases BP

A double-blind, placebo-controlled, crossover trial concluded that regular daily intake of 4 g acetaminophen increases systolic blood pressure (BP) in…

3 years ago

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