A study revealed that many middle-aged individuals free of cardiovascular risk factors (CVRF) have atherosclerosis. Atherosclerosis presence and extent was associated with low-density lipoprotein cholesterol (LDL-C) and glycosylated hemoglobin levels (HbA1c). The study evaluated 1,779 (45.0 ± 4.1 years old, 50.3% women) participants. CVRF freedom was defined as no current smoking and untreated blood pressure <140/90 mm Hg, fasting glucose http://www.onlinejacc.org/
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