No Benefit for Routine Iron Supplementation and Screening for Iron Deficiency Anemia in Pregnancy孕期常规补铁和筛查缺铁性贫血无益

A systematic review for the U.S. Preventive Services Task Force found inconclusive evidence that routine prenatal supplementation for iron deficiency anemia (IDA) improves maternal or infant clinical health outcomes, but supplementation may improve maternal hematologic indices. As an update of a 2006 systematic review by the USPSTF, the review included 12 supplementation trials. Routine maternal iron supplementation had inconsistent effects on rates of cesarean delivery, small size for gestational age, and low birth weight and no effect on maternal quality of life, gestational age, Apgar scores, preterm birth, or infant mortality. There were improvements in maternal hematologic indices and lower IDA incidence at term with supplementation in some studies. However, maternal iron supplementation did not affect infant iron status at 6 months. No difference in serious adverse effects was found between groups. Source: http://annals.org/为美国预防医学工作组所作的系统综述发现，没有肯定的证据表明，常规产前补铁用于缺铁性贫血改善产妇或婴儿的临床预后，但补铁可能改善产妇血液指标。作为对美国预防医学工作组2006年系统综述的更新，该综述包括了12个补铁试验。孕妇常规补铁对剖腹产，出生体积小和体重低，以及对孕妇生活质量，胎龄，Apgar评分，早产或婴儿死亡率的影响并不一致。某些研究中补铁改善了产妇血液指标和缺铁性贫血的发病率。然而，孕妇补铁并未影响婴儿6个月时铁的状态。严重不良反应补铁与否也无差异。来源：http://annals.org/