Mendelian Randomization


BP Causally Linked to AF

A Mendelian randomization (MR) study provided the evidence that the relationship between blood pressure (BP) and risk of atrial fibrillation (AF) might be causal. Genetic variants associated with the BP traits were retrieved from 299 024 subjects of European ancestry. Two-sample MR analyses were used to examine the potential causal association […]


Atlas on T2D Risk Factors

A meta-analyses and Mendelian randomization study identified causal risk factors for type 2 diabetes (T2D). The study found evidence of causal associations between 34 exposures (19 risk factors and 15 protective factors) and T2D. Insomnia was identified as a novel risk factor (OR 1.17). The other 18 risk factors were […]