Recent US stroke guidelines incorporate significant advances across the care continuum. Mobile Stroke Units (MSUs) are now recommended for their ability to accelerate thrombolysis. For suspected large vessel occlusion, bypassing to an endovascular thrombectomy (EVT)-capable center is endorsed when efficient. Intravenous thrombolysis (IVT) guidelines now include tenecteplase as non-inferior to […]
A Chinese multicenter, participant-blinded, randomized controlled trial found that remote ischemic conditioning (RIC)—a neuroprotective therapy involving twice-daily cuff inflation to 200 mmHg (four cycles of 5 minutes of ischemia followed by 5 minutes of reperfusion) for 7 days—significantly improved recovery in patients with acute ischemic stroke undergoing endovascular thrombectomy. Among […]
Two recent trials from China evaluated strategies to improve outcomes in patients with acute ischemic stroke treated within 4.5 hours of symptom onset. In the first open-label trial, 550 patients with large-vessel occlusion were randomized to receive either intravenous tenecteplase followed by endovascular thrombectomy or thrombectomy alone. Functional independence at […]
A case-crossover study in China suggests that hourly heat exposure is associated with increased risk of acute ischemic stroke (AIS). The time-stratified case-crossover study used a nationwide registry and included 82 455 adult AIS patients (mean age, 65.8 years; males 63.4%) hospitalized in the warm seasons (from April 1 to September […]