Daily Archives: July 10, 2025


Antidepressant Discontinuation Symptoms Not Clinically Significant

A systematic review and meta-analysis indicate that while antidepressant discontinuation is associated with a mild increase in physical symptoms, the average symptom burden does not reach the threshold for clinically significant discontinuation syndrome. Researchers examined symptoms using standardized measures such as the Discontinuation-Emergent Signs and Symptoms (DESS) scale and tracked […]