A special report revealed that genetics of autism is as complex as autism. The condition runs in families, but most of the relevant mutations identified so far arose spontaneously in the sperm or egg or after fertilization. The list of genes tied to autism continues to grow. Researches have expanded […]
A UK prospective population-based study of long-term antiplatelet treatment (predominantly daily aspirin 75 mg enteric coated) in secondary prevention of vascular disease showed that the severity, case fatality, and poor functional outcome of bleeds increased with age, and that in patients aged 75 years or older, most major upper gastrointestinal […]
A US cohort study suggested that maternal use of lithium during the first trimester was associated with an increased risk of cardiac malformations, including Ebstein’s anomaly (right ventricular outflow tract obstruction defects). The study included 1,325,563 pregnancies in women who delivered a live-born infant between 2000 and 2010. Cardiac malformations […]
A systematic review and network meta-analysis, which allowed the simultaneous comparison of multiple achieved systolic blood pressure (SBP) levels on clinical outcomes while preserving trial-level treatment randomization, indicates that treating patients to reduce SBP below currently recommended targets may significantly reduce risk of cardiovascular disease (CVD) and all-cause mortality, with […]