The US Food and Drug Administration warns moderation on licorice, or liquorice, a low-growing shrub mostly grown for commercial use in Greece, Turkey, and Asia. It is in black licorice and has been used as a treatment for heartburn, stomach ulcers, bronchitis, sore throat, cough and some infections caused by […]
A population-based, prospective cohort study revealed that a trajectory of increasing disability became significantly steeper after stroke but not after myocardial infarction (MI). The study included 5888 individuals 65 years or older from 1989 to 2013, mean age was 72.8 years; 2495 were male. During a mean follow-up of 13 […]
In a prospective, population-based cohort analysis, mitochondrial DNA copy number is independently associated with incident cardiovascular disease (CVD) and may have clinical utility in CVD risk classification. The analysis included 21 870 participants (20 163 free from CVD at baseline, mean age 62.4 years, and 54.7% women) from 3 studies with a […]
The American Heart Association scientific statement systematically reviewed data on the potential benefits of meditation on cardiovascular risk. Neurophysiological and neuroanatomical studies demonstrate that meditation can have long‐standing effects on the brain, which provide some biological plausibility for beneficial consequences on the physiological basal state, physiological responses, and on cardiovascular […]
Two studies showed that there is no benefit of supplemental oxygen in nonhypoxic patients with suspected myocardial infarction (MI) or acute stroke. A total of 6629 patients with suspected MI and an oxygen saturation of 90% or higher were randomly assigned to receive either supplemental oxygen (6 liters per minute […]
Two prospective cohort studies revealed that physical activity was associated with a lower risk of mortality both in the general population and in patients with stable coronary heart disease worldwide. The 1st study included 130 843 participants without pre-existing cardiovascular disease, and followed 6·9 years. Higher physical activity was associated with […]
An analysis of individual level pooled data from 10 prospective cohort studies concluded that obesity is associated with earlier onset of heart failure (HF), increased risk of HF; and greater proportion of life lived with HF in the context of shorter total longevity. A total of 170,205 adults free from […]
Findings from a prospective cohort study challenge current global dietary guidelines. A total of 135 335 individuals aged 35 to 70 years without cardiovascular disease (CVD) were enrolled between Jan 1, 2003, and March 31, 2013 from 613 communities in 18 low-income, middle-income, and high-income countries in seven geographical regions globally. […]
A randomized, double-blind trial of canakinumab targeting interleukin-1β innate immunity pathway revealed a significantly lower rate of recurrent cardiovascular events in patients of myocardial infarction (MI). The trial included 10,061 patients with previous MI and a high-sensitivity C-reactive protein （hsCRP） level of 2 mg or more per liter. Canakinumab (at […]
Patient-reported outcomes among participants who received intensive BP treatment were similar to those among participants who received standard treatment. A total of 9361 participants with hypertension at high risk for cardiovascular disease were randomly assigned to a systolic blood-pressure (SBP) target of less than 120 mm Hg or 140 mm […]