A cross-sectional study in Australia suggested that sitting-reduction strategies targeting increased standing, stepping, or both, may benefit cardio-metabolic health. Participants in 2011/12 wore a posture-based monitor (36–80 years, mean 57.9, 57% women; n = 698 with data). Associations of reallocating daily time from sitting/lying (sitting) to standing and stepping with cardio-metabolic risk biomarkers were analyzed. Adjusted for relevant confounders, sitting-to-standing reallocations were only significantly associated with approximately 2% lower fasting plasma glucose, 11% lower triglycerides, 6% lower total/HDL-cholesterol ratio, and 0.06 mmol/L higher HDL-cholesterol per 2 h/day. Sitting-to-stepping reallocations were only significantly associated with approximately 11% lower BMI, 7.5 cm lower waist circumference, 11% lower 2-h plasma glucose, 14% lower triglycerides, and 0.10 mmol/L higher HDL-cholesterol per 2 h/ day, while standing-to-stepping reallocations were only significantly associated with ∼10% lower BMI, 7 cm lower waist circumference, and 11% lower 2-h plasma glucose. High levels of sedentary time (sitting) have been linked detrimentally with cardiovascular disease, diabetes, and premature mortality. Source: http://eurheartj.oxfordjournals.org/澳大利亚的一项横断面研究表明，增加站立和/或步行而减少坐着的策略可能有利于心脏及代谢健康。参与者在2011/12年披戴体位显示器（36-80岁，平均57.9岁，57％为女性; N = 698有数据）。对每天从坐/卧（坐），代之以站立和步行与心脏及代谢风险指标的关系进行了分析。经校正相关的混杂因素，以站代坐2小时/天与空腹血糖降低约2％，甘油三酯降低11％，总/高密度脂蛋白胆固醇的比率降低6％，高密度脂蛋白胆固醇增高0.06 毫摩尔 / 升显著相关。以步行代坐2小时/天与BMI降低约11％，腰围减少7.5厘米，2小时血糖低11％，甘油三酯低14％，和HDL-胆固醇增高0.10毫摩尔/ L显著相关，而以步行代站2小时/天则与BMI降低约10％，腰围减少7厘米，2小时血糖低11％显著相关。长期不活动（坐）与心血管病，糖尿病和早死有关。来源：http://eurheartj.oxfordjournals.org/
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