A prospective cohort study in UK concluded that there was a dose–response association between the extent of pain at baseline and insomnia onset at 3 years that was substantially mediated by physical limitation and reduced social participation. Targeting physical limitation and social participation in older people with pain may buffer co-morbid insomnia, reducing the overall disease burden. The study was conducted involving 6676 individuals ≥50 years of age who completed questionnaires at baseline and a 3-year follow-up. Participants were classified into none, some and widespread pain. Some and widespread pain increased the risk of insomnia onset at 3 years, after adjusting for age, gender, socio-economic class, education, anxiety, depression, sleep and co-morbidity at baseline. The combination of physical limitation and reduced social participation explained up to 68% of the effect of some pain on insomnia onset and 66% of the effect of widespread pain on insomnia onset. Pain is highly prevalent among older adults, with worse health outcomes found in those with co-morbid insomnia. Source: http://rheumatology.oxfordjournals.org英国一项前瞻性群组研究的结论是，研究最初的疼痛程度与3年时基本上由身体活动受限和社交参与减少导致的失眠发病之间存在量效关系。针对老年疼痛患者的活动受限和社交参与减少可缓冲并发失眠，降低整体疾病负担。该研究包括6676名年龄≥50岁，完成了最初的问卷调查和3年随访的参与者。参与者被分为无，局部和广泛性疼痛。 经校正年龄，性别，社会经济阶层，教育，焦虑，抑郁，睡眠和合并症后，局部和广泛性疼痛增加3年时失眠发病的风险。活动受限和社交参与减少结合可解释高达68％的局部性疼痛对失眠发病的影响，及66％的广泛性疼痛对失眠发病的影响。疼痛在老年人中非常普遍，并发失眠者预后更差。来源：http://rheumatology.oxfordjournals.org<!–:–
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