Acetaminophen


Sodium-containing Acetaminophen Linked to CVD Risk

Two UK cohort studies among individuals with and without high blood pressure (HBP) found that the initiation of sodium-containing acetaminophen was associated with a significant higher risk of incident cardiovascular disease (CVD, including myocardial infarction, stroke, and heart failure) and all-cause mortality than non-sodium-containing acetaminophen. The studies used marginal structural […]


Acetaminophen Increases BP

A double-blind, placebo-controlled, crossover trial concluded that regular daily intake of 4 g acetaminophen increases systolic blood pressure (BP) in individuals with hypertension by ≈5 mm Hg when compared with placebo. The trial randomized 110 patients of high BP to receive 1 g acetaminophen 4× daily or matched placebo for 2 […]