A systematic review and dose-response meta-analysis revealed that a consistent finding of an immediately higher cardiovascular risk following any alcohol consumption but by 24 hours, only heavy alcohol intake conferred continued risk. A total of 29457 participants in 23 studies were included. Moderate alcohol consumption was associated with an immediately higher cardiovascular risk that was attenuated after 24 hours, and even protective for myocardial infarction and hemorrhagic stroke, and protective against ischemic stroke within one week. In contrast, heavy alcohol drinking was associated with higher cardiovascular risk in the following day and week. Heavy episodic drinking has harmful effects, even if individuals who binge only drink one or two days per week, resulting in the same average alcohol intake per week that is known to yield cardioprotective benefits. Source: http://circ.ahajournals.org/
一项系统性综述和量效关系荟萃分析显示，无论饮用任何酒类，一致的结果是紧接着心血管风险较高，但24小时后，只有大量饮酒风险持续。共包括23项研究中29457名参与者。适度饮酒后紧接着心血管风险较高，24小时后风险减弱，甚至对心肌梗死和出血性中风具有保护性，在一个星期内对缺血性脑卒中亦具有保护性。相反，大量饮酒则与次日/周较高的心血管风险有关。偶尔酗酒亦有害，即便每周只狂饮一，两天者，且周平均酒精摄入量与已知有心脏保护作用的周平均酒精摄入量相同。来源：http://circ.ahajournals.org/
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