FDA Gets Tougher on NSAIDs Cardiovascular RisksFDA对非阿司匹林非甾体抗炎药的心血管病风险更严格

Based on a comprehensive review of new safety information, FDA is strengthening an existing label warning that non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) increase the chance of a heart attack or stroke. FDA is requiring updates to the drug labels of all prescription and over-the-counter (OTC) NSAIDs. The risk of heart attack or stroke can occur as early as the first weeks of using an NSAID. The risk may increase with longer use and higher doses of the NSAID. In general, patients with heart disease or risk factors for it have a greater likelihood of heart attack or stroke following NSAID use than patients without these risk factors. The risk of heart failure is also increased. Source: http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm454141.htm?source=govdelivery&utm_medium=email&utm_source=govdelivery根据新的安全信息所做的全面审查，FDA要加强现有的标签警告，非阿司匹林非甾体抗炎药（NSAIDs）增加心脏病发作或中风的机会。 FDA要求更新所有处方和零售NSAIDs药品标签。心脏病发作或中风的风险在使用NSAIDs的头几周即可显现。随着使用时间的延长和剂量的增高，风险可能会增加。一般情况下，有心脏病及其危险因素的患者比没有这些危险因素的患者使用NSAIDs心脏病发作或中风可能性更大。心衰的风险也增加。来源：http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm454141.htm?source=govdelivery&utm_medium=email&utm_source=govdelivery