Adverse Effects of Obesity and High Blood Pressure on Heart Begin in Childhood肥胖和高血压对心脏的不良影响始于童年

The findings of a community-based, longitudinal study in the US indicate that the adverse influence of excessive adiposity and elevated blood pressure (BP) levels on left ventricular hypertrophy (LVH) begins in childhood and accumulate over time. The study consisted of 1,061 adults, age 24 to 46 years, who had been examined 4 or more times for body mass index (BMI) and blood pressure (BP) starting in childhood, with a mean follow-up of 28.0 years. Higher values of BMI and systolic and diastolic BP in childhood and adulthood were significantly associated with higher LV mass index and LVH including eccentric hypertrophy (EH) and concentric hypertrophy. BMI had a consistently and significantly greater influence on EH than did measures of BP. Source: http://content.onlinejacc.org/美国一个基于社区的追踪研究结果显示，过度肥胖和高血压对左室肥大（LVH）的不利影响始于童年，并随时间累积。这项研究包括了1,061名成人，年龄24〜46岁，从童年开始检查了4次以上的体重指数（BMI）和血压，平均随访28.0年。 童年和成年期BMI及收缩压和舒张压值较高与较高的左心室质量指数和左心室肥大均显著相关，包括离心性肥大（EH）和向心性肥大。BMI比血压对EH的影响更为显著。来源：http://content.onlinejacc.org/