Vitamin D Deficiency Associated with Dementia痴呆与维生素D缺乏有关

A prospective observational study in the US found that vitamin D deficiency is associated with a substantially increased risk of all-cause dementia and Alzheimer disease. The study included 1658 elderly ambulatory adults free from dementia, cardiovascular disease, and stroke between 1992–1993 and 1999 with a mean follow-up of 5.6 years. 171 participants developed all-cause dementia, including 102 cases of Alzheimer disease. The risk of all-cause dementia and Alzheimer disease markedly increased in participants who were severely vitamin D deficient (serum 25-hydroxyvitamin D美国一项前瞻性观测研究发现，维生素D缺乏与各种原因的痴呆和阿尔茨海默病的风险大幅增加有关。该研究包括1992-1993年至1999年间1658名非卧床的老人且无老年痴呆症，心血管病和中风，平均随访5.6年。 171名参加者发生了各种原因的痴呆症，其中包括102例阿尔茨海默病。与具有足够浓度维生素D者（血清25 – 羟维生素D≥50纳摩尔/升）相比，各种原因的痴呆和阿尔茨海默病的风险在严重的维生素D缺乏者（