NSAIDs May Increase Risk of Atrial Fibrillation非类固醇消炎药可能增加房颤的风险

A prospective community-based follow-up study of 8423 elderly individuals in Netherlands found that use of non-steroidal anti-inflammatory drugs (NSAIDs) was associated with an increased risk of atrial fibrillation (AF) . The study was based on data from the Rotterdam Study involving adults 55 and older, mean age was 68.5 years and 58% were women. During a mean follow-up of 12.9 years, current use of NSAIDs and recent use (within 30 days after discontinuation of NSAIDs) were associated with an increased risk of AF compared with never-use adjusted for age, sex and cardiovascular risk factors. Other recent studies also have identified a link between NSAIDs and AF.荷兰一项对8423名老年人的前瞻性以社区为基础的随访研究发现，使用非类固醇消炎药（NSAIDs）与心房纤颤（AF）的风险增加有关。该研究是基于鹿特丹研究的数据，年龄55岁以上，平均68.5岁，58％为女性。在平均随访12.9年中，经调整年龄，性别和心血管病危险因素，正在用NSAIDs和近期用过NSAIDs（停药后30天以内）与未用者相比房颤的风险均增加。最近其他一些研究也发现了NSAIDs和AF之间的联系。