A prospective study revealed that active smoking and cumulative cigarette exposure were associated with subtle alterations in left ventricular (LV) structure and function. The study included 4580 participants free of overt coronary artery disease, heart failure, and significant valvular disease, who underwent transthoracic echocardiography. Compared with non-smokers, current smokers as well as estimated pack-years and years of smoking, measures of cumulative cigarette exposure, were associated with greater LV mass index, LV mass/volume ratio, higher prevalence of LV hypertrophy, and worse diastolic function, after adjusting for potential confounding factors. In contrast, former smokers showed similar echocardiographic features when compared with non-smokers. It has been known that smoking is a major risk factor for atherosclerosis and heart attacks. Source: http://circimaging.ahajournals.org/
一项前瞻性研究显示，吸烟及累积香烟接触与左心室结构和功能改变有微妙关联。该研究包括4580名无明显冠心病，心衰和显著瓣膜病，经超声心动图检查的参与者。与非吸烟者相比，并经校正潜在的混杂因素，吸烟者以及估计的包年和吸烟年数（累积香烟接触的指标），与较大的左室质量指数，左室质量/体积比，较高的左心室肥厚发病率，且较差的舒张功能相关。相比之下，曾经吸烟者与非吸烟者相比显示类似的超声心动图特征。已知吸烟是动脉粥样硬化和心脏病发作的主要危险因素。来源：http://circimaging.ahajournals.org/
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