The American College of Physicians recommends that clinicians select between either cognitive behavioral therapy or second-generation antidepressants to treat patients with major depressive disorder after discussing treatment effects, adverse effect profiles, cost, accessibility, and preferences with the patient. The guideline is based on a systematic review of published, English-language, randomized, controlled trials from 1990 through September 2015 identified using several databases and through hand searches of references of relevant studies. Interventions evaluated include psychotherapies, complementary and alternative medicines (including acupuncture, ω-3 fatty acids, S-adenosyl-l-methionine, St. John’s wort), exercise, and second-generation antidepressants. Evaluated outcomes included response, remission, functional capacity, quality of life, reduction of suicidality or hospitalizations, and harms. Source: http://annals.org/
美国医师学院建议,与患者讨论过治疗效果,不良反应,费用,方便与否,和个人喜好后,临床医生可选择认知行为疗法或第二代抗抑郁药治疗严重抑郁症患者。该建议是基于对利用若干数据库,并通过相关研究参考文献的手工检索鉴定的,从1990年至2015年9月间英语文献中随机对照试验的系统性审查。评估的干预措施包括心理治疗,补充和替代疗法(包括针灸,ω-3脂肪酸,S-腺苷-L-蛋氨酸,圣约翰草),运动,和第二代抗抑郁药。评估的指标包括疗效,缓解,功能水平,生活质量,减少自杀或住院,以及危害。来源:http://annals.org/
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