Categories: 精神障碍

Patches of Disorganization Found in the Brain Structure in Autistic Kids自闭症儿童的大脑中发现斑片性结构紊乱

Focal patches of abnormal laminar cytoarchitecture and cortical disorganization of neurons, but not glia, in prefrontal and temporal cortical tissue from autopsied brains in 10 of 11 children with autism and in 1 of 11 unaffected children age 2 to 15. The location of those patches corresponded to regions mediating the functions that are disturbed in autism: social, emotional, communication, and language functions. Autism involves early brain overgrowth and dysfunction, which is most strongly evident in the prefrontal cortex. The findings tend to reinforce the notion that autism is prenatal in origin.尸检在11名自闭症儿童中的10名的额叶和颞叶皮层组织发现局部斑片性异常层状细胞结构和皮质神经元紊乱,而非神经胶质细胞。类似的发现仅存在于11名未受影响儿童中的1名。儿童年龄2岁至15岁。这些斑片所在的位置与涉及自闭症功能紊乱的区域相对应,如社交,情感,沟通和语言功能。自闭症涉及早期脑过度生长和功能障碍,尤以前额叶皮层最为明显。该发现有助于强化自闭症是先天性起源的概念。

hyangiu

近期博文

生命早期限制糖对2 型糖尿病和高血压有保护作用

比较糖配给结束前后受孕的英国成…

2 周 ago

寒冷天气与心梗风险较高有关

一项中国全国性病例交叉研究显示…

3 周 ago

夜晚较亮、白天较暗预示死亡风险较高

一项前瞻性队列研究表明,暴露于…

1 月 ago

正念减压疗法与依他普仑治疗焦虑症疗效相当

美国一项随机临床试验显示,临床…

1 月 ago

2024 年欧洲心脏病学会高血压指南的关键信息

全球范围内患高血压者正在增加。…

3 月 ago

This website uses cookies.