A retrospective cohort study concluded that increasing obesity is contributing to the rising incidence of type 2 diabetes (T2D), but not type 1 diabetes (T1D), among UK children and young adults. The study included 369,362 participants aged 2-15 y between 1994 and 2013. There were 654 and 1318 incident cases of T2D and T1D, respectively. The incidence of T2D increased in both overweight (85th-95th percentile for age- and sex-specific BMI) and obese (≥95th percentile) individuals from 1994 to 2013. Obese individuals, who constituted 47.1% of T2D cases, had a markedly higher risk of incident T2D (odds ratio, 3.75) with an incidence rate ratio of 4.33, compared with normal BMI category. There was no positive linear association between obesity (higher BMI) and incident T1D. The findings are consistent with much of the literature. Source: https://academic.oup.com/
回顾性群组研究得出结论，肥胖的增加促使英国儿童和年轻人中2型糖尿病的发病率上升，而非1型糖尿病。 该研究包括1994至2013年间，年龄2-15岁的369,362名参与者，分别发生了654例和1318例2型和1型糖尿病。 从1994年到2013年，超重（年龄和性别特异性体重指数的第85-95百分位数）和肥胖（≥95百分位数）者2型糖尿病发病率增加了。与体重指数正常者相比，占2型糖尿病病例47.1％的肥胖者2型糖尿病发生率显着升高（风险比为3.75），发生率比例为4.33。 肥胖（体重指数较高）与1型糖尿病之间则无正线性相关。 这些发现与许多文献一致。 来源：https://academic.oup.com/