Fish oil supplementation (omega-3 polyunsaturated fatty acids eicosapentaenoic acid plus docosahexaenoic acid) is still recommended by the American Heart Association for patients with prevalent coronary heart disease as well as heart failure without preserved left ventricular function. The recommendations came after reviewing large randomized controlled trials of supplementation with major clinical cardiovascular disease end points; meta-analyses were considered secondarily. However, there is no recommendation for primary prevention with fish oils. Source: http://circ.ahajournals.org/
美国心脏协会仍然建议有冠心病以及无左心室功能储备的心衰患者补充鱼油(ω-3多不饱和脂肪酸二十碳五烯酸和二十二碳六烯酸)。 这些建议是在审查了以主要临床心血管病为终点的大型随机对照补充试验后做出的; 荟萃分析作为次要参考。 然而,不建议鱼油用作一级预防。 来源:http://circ.ahajournals.org/