A nationwide prospective study in China revealed that diabetes was associated with increased mortality among adults in China. Although diabetes was more common in urban areas, it was associated with greater excess mortality in rural areas. The study included 512 869 adults aged 30 to 79 years from 10 regions in China, who were recruited between June 2004 and July 2008 and were followed up until January 2014. The mean age was 51.5 years, 59% were women, and 5.9% had diabetes (4.1% in rural areas, 8.1% in urban areas). During 3.64 million person-years of follow-up, there were 24 909 deaths, including 3384 among individuals with diabetes. Compared with adults without diabetes, individuals with diabetes had a significantly increased risk of all-cause mortality (1373 vs 646 deaths per 100 000; adjusted mortality rate ratio [RR] 2.00), which was higher in rural areas than in urban areas (RR 2.17 vs. 1.83). Presence of diabetes was associated with increased mortality from ischemic heart disease (3287 deaths; RR 2.40), stroke (4444 deaths; RR 1.98), chronic liver disease (481 deaths; RR 2.32), infections (425 deaths; RR 2.29), and cancer of the liver (1325 deaths; RR 1.54), pancreas (357 deaths; RR 1.84), female breast (217 deaths; RR 1.84), and female reproductive system (210 deaths; RR 1.81). For chronic kidney disease (365 deaths), the RR was higher in rural areas than in urban areas (18.69 vs. 6.83). Among those with diabetes, 10% of all deaths (16% rural; 4% urban) were due to definite or probable diabetic ketoacidosis or coma (408 deaths). Source: http://jamanetwork.com/
中国一项全国的前瞻性研究显示，糖尿病与中国成人死亡率升高相关。虽然糖尿病在城市更常见，但与更高的农村死亡率有关。该研究包括来自中国10个地区的512869名30至79岁的成年人，从2004年6月至2008年7月间开始，随访至2014年1月。平均年龄51.5岁，59％为女性，5.9％为糖尿病（农村4.1％，城市8.1％）。在364万人年的随访中，24909例死亡，其中糖尿病患者3384例。与无糖尿病的成人相比，糖尿病患者的全因死亡风险显着增加（每十万人死亡1373比646例;校正死亡率比值 2.00），农村高于城市（2.17对1.83）。糖尿病与下列病死率升高有关：缺血性心脏病（死亡3287例; 比值 2.40），中风（死亡4444例; 比值 1.98），慢性肝病（死亡481例; 比值 2.32），感染（死亡425例; 比值 2.29；以及下列癌症：肝脏（死亡1325例; 比值 1.54），胰腺（死亡357例; 比值 1.84），女性乳房（死亡217例; 比值 1.84）和女性生殖系统（死亡210例; 至 1.81）。对于慢性肾脏病（死亡365例），农村的比值高于城市（18.69比6.83）。糖尿病患者中，10％（农村 16％; 城市4%）死于确定或可能的糖尿病酮症酸中毒或昏迷（死亡408例）. 来源：http://jamanetwork.com/