A randomized crossover study showed that breaking sitting with standing and light-intensity walking effectively improved 24 h glucose levels and improved insulin sensitivity in individuals with type 2 diabetes (T2D) to a greater extent than moderate to vigorous exercise. The study included 19 patients with T2D (13 men/6 women, 63 ± 9 years old) who were not using insulin, each followed three regimens under free-living conditions, lasting 4 days each: (1) Sitting: 14 h sitting/day; (2) Exercise: 1.1 h/day of sitting replaced by moderate- to vigorous-intensity cycling (at an intensity of 5.9 metabolic equivalents); and (3) Sit Less: 4.7 h/day of sitting replaced by 2.5 h standing and 2.2 h light-intensity walking. Meals were standardized during each intervention. The incremental AUC (iAUC) for 24 h glucose (mean ± SEM) was significantly lower during the Sit Less intervention than in Sitting (1263 ± 189 vs 1974 ± 324 min × mmol/l), and was similar between Sit Less and Exercise (Exercise: 1383 ± 194 min × mmol/l). Sit Less significantly reduced insulin resistance compared with Exercise as well as Sitting. The findings suggest that the duration of non-sitting activities may be more beneficial than the intensity of these activities. Source: http://link.springer.com/
随机交叉研究显示，以间断站立或轻度步行代替坐着，在更大程度上比中度至剧烈运动更有效地改善2型糖尿病者24小时血糖水平和改善胰岛素敏感性。该研究包括19名未使用胰岛素的2型糖尿病患者（13名男性/ 6名女性，63±9岁），每人在自由生活条件下遵循三种方案，每次持续4天：（1）坐着：坐14小时/天; （2）锻炼：以1.1小时/天中 – 高强度自行车（强度为5.9代谢当量）代替坐着;和（3）少坐：以2.5小时站立和2.2小时轻度步行代替4.7小时/天的坐着。每次干预期间膳食均标准化。在少坐干预期间，24小时血糖（平均值±标准误）的增量AUC（iAUC）显着低于坐着（1263±189 与1974±324分×毫摩尔 / 升），而少坐与锻炼相当：（锻炼：1383±194分×毫摩尔 / 升）。少坐与锻炼或坐着相比，胰岛素抵抗显着减弱。研究结果提示，活动（非坐着）的持续时间可能比这些活动的强度更有益。来源：http://link.springer.com/