A British study found that People with elevated BP are at increased risk of diabetes. The strength of the association declined with increasing body mass index and age. The study identified a cohort of 4.1 million adults, free of diabetes and cardiovascular disease, by using validated linked electronic health records. Analyses were complemented by a meta-analysis of prospective studies that reported relative risks of new-onset diabetes per unit of systolic blood pressure (SBP). Among the overall cohort, 20 mm Hg higher SBP and 10 mm Hg higher diastolic BP were associated with a 58% and a 52% higher risk of new-onset diabetes, respectively. There was no evidence of a nadir to a baseline BP of 110/70 mm Hg. The strength of the association per 20 mm Hg higher SBP declined with age and with increasing body mass index. Estimates were similar even after excluding individuals prescribed antihypertensive or lipid-lowering therapies. Systematic review identified 30 studies with 285,664 participants and 17,388 incident diabetes events. The pooled relative risk of diabetes for a 20 mm Hg higher usual SBP across these studies was 1.77. The findings support the hypothesis that hypertension is an independent risk factor for type 2 diabetes. Source: http://content.onlinejacc.org/
英国一项研究发现，血压高者糖尿病的风险增加。而相关强度随体重指数和年龄增加而下降。该研究通过验证的相关电子医疗记录确定了410万无糖尿病及心血管病的成年人群组。分析并辅之以对报导了每单位收缩压新发糖尿病相对风险的前瞻性研究的荟萃分析。该群组中收缩压每升高20毫米汞柱，或舒张压每升高10毫米汞柱，则新发糖尿病的风险分别增加58％和52％。低至110/70毫米汞柱的基线血压而无证据是最低点。收缩压每升高20毫米汞柱（与新发糖尿病风险）的关联强度随着年龄和体重指数增加而下降。排除有降压或降脂治疗处方个体后估计仍相似。系统综述确定了30项研究，285664例参与者和17,388例发生糖尿病的事件。总体而言这些研究中通常收缩压升高20毫米汞柱则糖尿病的综合相对风险值为1.77。这些发现支持高血压是2型糖尿病独立危险因素的假设。来源：http://content.onlinejacc.org/