A prospective cohort study of 25 848 men in the US found that recent sildenafil use at baseline was significantly associated with an increased risk of subsequent melanoma, but not squamous cell carcinoma and basal cell carcinoma. Moreover, erectile function itself was not associated with an altered risk of melanoma. Ever use of sildenafil was also associated with a higher risk of melanoma. Source: http://archinte.jamanetwork.com/article.aspx?articleid=1857095美国一项包括25848人的前瞻性群组研究发现，近期使用西地那非 （万艾可）与随后黑色素瘤风险的增加有关，而非鳞状细胞癌和基底细胞癌。此外，勃起功能障碍 （万艾可的适应症）本身并不影响黑色素瘤风险。曾经使用西地那非者黑色素瘤的风险也较高。来源: http://archinte.jamanetwork.com/article.aspx?articleid=1857095
