Aspirin for Primary Prevention: Yes or NO?阿司匹林用于一级预防：是或否？

The FDA has reviewed the available data and does not believe the evidence supports the general use of aspirin for primary prevention of a heart attack or stroke. In fact, there are serious risks associated with the use of aspirin, including increased risk of bleeding in the stomach and brain, in situations where the benefit of aspirin for primary prevention has not been established. The U.S. Preventive Services Task Force recommends the use of aspirin for men ages 45 to 79 years when the potential benefit of a reduction in myocardial infarction outweighs the potential harm of an increase in gastrointestinal hemorrhage and for women ages 55 to 79 years when the potential benefit of a reduction in ischemic stroke outweighs the potential harm of an increase in gastrointestinal hemorrhage. The American Heart Association recommends using aspirin for primary prevention in patients with an elevated risk for coronary disease. There is a consensus that the benefits of aspirin outweigh the risks for secondary prevention. Source: http://www.medpagetoday.com/美国食品药物管理局审阅了现有的资料，并不相信有证据支持阿司匹林广泛应用于心脏病发作或中风的一级预防。事实上，在阿司匹林用于一级预防的益处尚未确立的情况下，有与阿司匹林相关的严重风险，包括胃和大脑出血的风险增加。年龄45 〜79岁的男性在心肌梗塞减少的益处和55至79岁的女性在缺血性脑卒中减少的益处远远超过消化道出血增加的潜在危害的情况下，美国预防医学工作组建议应用阿司匹林。美国心脏协会则建议冠心病高危患者应用阿司匹林进行一级预防。阿司匹林用于二级预防的益处大于风险则是公认的。来源：http://www.medpagetoday.com/