After reviewing 23 studies including 21 randomized controlled trials, the USPSTF found that daily low-dose aspirin in women at high risk for preeclampsia beginning as early as the second trimester prevented clinically important health outcomes such as preeclampsia, intrauterine growth restriction, and preterm birth. No harms were identified, but long-term evidence was limited.经回顾23项研究，包括21项随机对照试验之后，美国预防医学工作组发现，先兆子痫高危妇女从孕中期开始每天服用低剂量阿司匹林可预防有重要临床意义的状况，如先兆子痫，胎儿宫内生长受限，以及早产。未发现不良后果，但长期证据有限。
