- Annual mammography failed to reduce breast cancer mortality compared with physical examination or routine care, according to 25-year follow-up data from a Canadian screening program in 89835 women ages 40 to 59. Overall, 22% (106/484) of screen detected invasive breast cancers were over-diagnosed, representing one over-diagnosed breast cancer for every 424 women who received mammography screening in the trial.
加拿大对89835名年龄40至59岁妇女的筛查项目经25年的随访数据显示，与体检或常规治疗相比，年度乳房X光检查未降低乳腺癌死亡率。总体来说，筛检发现的22％（106/484）的侵袭性乳腺癌属过度诊断，代表每筛查424名妇女就有一个被过度诊断为乳腺癌。